.Nature Medicine, Published online: 18 September 2024 doi:10.1038/ s41591-024-03300-3Genomic and epidemiologic evaluations uncovered that an unique reassortant viral family tree of the Oropouche infection, which has actually been actually flowing in the western side Amazon.com region of Brazil for about a decade, is associated with the latest human episodes between 2022 and 2024.